ACEM Fellowship
MRI Protocols

MRI Protocols

T1 vs. T2 images

  • T1 images = 1 type of tissue is bright white = FAT
  • T2 images = 2 types of tissue are bright white = FAT and WATER

T1 images

  • Because fat is bright, subcutaneous fat and bone marrow will appear bright white
  • Conversly, CSF is fat free and will show as black
  • Bone cortex is black as it contains no free protons
  • Pathology
    • Loss of bright white bone marrow in vertebral bodies indicates increased water content and suggests pathology such as trauma, infection or cancer
T1 image of prostatic metastases. Low signal areas of vertebral bodies are mets.

T2 images

  • Anything that is bright on T2 but black on T1 is water
  • CSF will appear white in addition to subcutaneous fat and bone marrow
  • Bone cortex is black as it contains no free protons
  • Pathology
    • Increased brightness within the vertebral body indicates increased water content and suggests pathology such as trauma, infection or cancer

STIR images

  • STIR (Short Tau Inversion Recovery) suppresses signal from fatty tissues so ONLY water is bright
  • Abnormal low signal on T1 (reduced fat content) and increased signal on STIR (increased water content) suggests pathology such as discitis

FLAIR images

  • FLAIR (Fluid Attenuated Inversion Recovery) is used for brain imaging
  • Signal from free fluid (such as CSF) is suppressed
  • Comparing this to T2 allows a high signal area on T2 (?CSF) to be compared to a high signal on these images indicating infection, tumour or areas of demyelination

DWI images and ADC images

  • DWI (Diffusion Weighted Imaging) and ADC (Apparent Diffusion Coefficient) images are viewed together
  • High signal on DWI and low signal on ADC indicates restricted diffusion e.g. infarction, cancer or abscess

Gadolinium contrast

  • Produces a very high signal
  • Abnormal tissue such as inflamed, cancerous tissue is often more vascular and enhances post-contrast

Specific pathologies

Cauda equina: Sagittal T2 showing lumbar disc herniation. Water and fat appear white while the disc appears dark.

Central cord syndrome

Sagittal T2 showing central cord lesion with increased signal owing to increased water content within cord due to trauma/haematoma/inflammation

Last Updated on June 12, 2024 by Andrew Crofton